nzyme-substrate complex Tyr 96 PeAYOYeY Phe 87 va|247 Asp 297 Leu 244 Camphor(substrate) va|295 Heme FIGURE 8.5 Structure of an enzyme-substrate complex(Left) The enzyme cytochrome P-450 is illustrated bound to its substrate camphor. (Right) In the active site the substrate is surrounded by residues from the enzyme. Note also the presence of a heme cofactorEnzyme-substrate complex