Chapter 9 Catalytic Strategies 8 14 P-loop domains and mechanisms are common.Why? Ans: These structures are able to undergo large changes in conformation during the binding of NTP and its hydrolysis,thus permitting structural diversity that can account for varied specificity. Section:9.3 15 Why is a metal ion required for the activity of most NTP-dependent enzymes? Ans:The enzyme does not bind the NTP,but binds the complex consisting of the metal ion- nucleotide group. Section:9.4Chapter 9 Catalytic Strategies 8 14 P-loop domains and mechanisms are common. Why? Ans: These structures are able to undergo large changes in conformation during the binding of NTP and its hydrolysis, thus permitting structural diversity that can account for varied specificity. Section: 9.3 15 Why is a metal ion required for the activity of most NTP-dependent enzymes? Ans: The enzyme does not bind the NTP, but binds the complex consisting of the metal ion- nucleotide group. Section: 9.4