CTP inhibits ATCase John Gerharti和Arthur Pardee.发现ATCase受CTP抑制 CTP是嘧啶合成途径的最终产物。 CTP浓度高，则酶催化活性降低。 0.5 1.0 [CTP],mM Figure 10.2 CTP inhibits ATCase.Cytidine triphosphate,an end product of the pyrimidine synthesis pathway,inhibits aspartate transcarbamoylase despite having little structural similarity to reactants or products.CTP inhibits ATCase Figure 10.2 CTP inhibits ATCase. Cytidine triphosphate, an end product of the pyrimidine synthesis pathway, inhibits aspartate transcarbamoylase despite having little structural similarity to reactants or products. John Gerhart和Arthur Pardee发现ATCase受CTP抑制 • CTP是嘧啶合成途径的最终产物。 • CTP浓度高，则酶催化活性降低