Immune Network Theory x Idiotypic network(Jerne, 1974) xB cells co-stimulate each other o Treat each other a bit like antigens x Creates an immunological memory Suppre Negative response Paratope Ag Idiotope 3 Antibody Activation Positive responseImmune Network Theory Idiotypic network (Jerne, 1974) B cells co-stimulate each other Treat each other a bit like antigens Creates an immunological memory 1 2 3 Ag Activation Positive response Suppression Negative response Antibody Paratope Idiotope