Hodgkins lymphoma 1. Presence of the distinctive neoplastic R-s cells and non-neoplastic cells usually greatly outnumber the tumor cells 2. Studies show that it is a tumor come of b lymphomacytesHodgkin’s lymphoma 1. Presence of the distinctive neoplastic R-S cells and non-neoplastic cells usually greatly outmumber the tumor cells. 2. Studies show that it is a tumor come of B lymphomacytes