上游充通大学 SHANGHAI JIAO TONG UNIVERSITY Tissue Engineering Tissue damage or organ failure resulting from injury or disease is a major health care problem,and the transplantation of tissues or organs is severely limited.Since 1988,Tissue engineering is a new but rapidly growing field that uses implanted cells,scaffolds,and biologically active molecules to replace or repair injured or diseased tissues and organs. Nervous tissue:Internal communication Brain,spinal cord,and nerves Cell source Novel chemistries Engineering cells iPSCs 器心 Engineering Muscle tissue:Contracts to cause movement Muscles attached to bones (skeletal) Adult stem Muscles of heart(cardiac) Muscles of walls of hollow organs(smooth) cells Growth factors aterials Epithelial tissue:Forms boundaries between different environments,protects,secretes,absorbs,filters Lining of Gl tract organs and other hollow organs Skin surface (epidermis) Genetic tools Progress in tissue engineering Biomechanics CRISPR-Cas9 Connective tissue:Supports,protects,binds other tissues together Bones Decellularized Tendons Fat and other soft padding tissue Self assembly 3D printing organs 日日日且 Engineering tissue architecture Journal of Biomedical Materials Research banner,53(6),20003 Tissue Engineering Tissue damage or organ failure resulting from injury or disease is a major health care problem, and the transplantation of tissues or organs is severely limited. Since 1988, Tissue engineering is a new but rapidly growing field that uses implanted cells, scaffolds, and biologically active molecules to replace or repair injured or diseased tissues and organs. Journal of Biomedical Materials Research banner, 53(6),2000