Some historical facts about our understanding on oxidative phosphorylation 1930s: Pyruvate was known to be completely oxidized to co2 via the citric acid cycle(with O2 consumed) 1930s: NAD+ and Fad were found to be e carriers between metabolites and the respiratory chain 1930s: Role of atp and general importance of phosphorylation in bioenergetics were realizedSome historical facts about our understanding on oxidative phosphorylation • 1930s: Pyruvate was known to be completely oxidized to CO2 via the citric acid cycle (with O2 consumed). • 1930s: NAD+ and FAD were found to be e￾carriers between metabolites and the respiratory chain. • 1930s: Role of ATP and general importance of phosphorylation in bioenergetics were realized