7.6 Accuracy depends AMP on proofreading Cognate tRNA Non cognate tRNA associates rapidl associates slow dissociates slowly dissociates rapidly AMP AMP Figure 7.15 Recognition of the Cognate tRNA chan correct trna by synthetase is in conformati controlled at two steps. First, the enzyme has a greater affinity for without change in conformation occurs slowly AMP its cognate tRNA. Second, the aminoacylation of the incorrect Aminoacylation occurs rapidl tRNa is very slow NH2 RCH 消当 AMPAMPFigure 7.15 Recognition of the correct tRNA by synthetase is controlled at two steps. First, the enzyme has a greater affinity for its cognate tRNA. Second, the aminoacylation of the incorrect tRNA is very slow. 7.6 Accuracy depends on proofreading