4.教学方法 Firstly,ask student could combine theory and knowledge frame between pharmaceutics and biopharmaceutics& pharmacokinetics,through typical case introduction.Secondly,enhance the understanding of new drug development process, thereafter to construct the pharmaceutical knowledge system. 5.教学评价 Quick summary test and discuss selected frequently asked questions. Section 6.Drugs affecting the immune system 1.教学目标 Learn the most commonly used anti-inflammatory drugs. Have a general concept about the applicable indications for each class of anti-inflammatory drug,as well as their side effects, especially over long-term use. 2.教学重难点 SAR studies for glucocorticoids lead to development of generations of systemic drugs with improved selectivity and reduced side effects(to some degree). Topical,inhaled and intranasal glucocorticoids require very different PK properties.These were achieved with both structural modification and formulation change. Toxicity of acetaminophen is related to its metabolism. Major side effect of NSAID is the GI toxicity.Some are designed as prodrugs to reduce this side effect. selective NSAID has significantly reduced GI toxicity.4.教学方法 Firstly, ask student could combine theory and knowledge frame between pharmaceutics and biopharmaceutics & pharmacokinetics, through typical case introduction. Secondly, enhance the understanding of new drug development process, thereafter to construct the pharmaceutical knowledge system. 5.教学评价 Quick summary test and discuss selected frequently asked questions. Section 6. Drugs affecting the immune system 1.教学目标 Learn the most commonly used anti-inflammatory drugs. Have a general concept about the applicable indications for each class of anti-inflammatory drug, as well as their side effects, especially over long-term use. 2.教学重难点 SAR studies for glucocorticoids lead to development of generations of systemic drugs with improved selectivity and reduced side effects (to some degree). Topical, inhaled and intranasal glucocorticoids require very different PK properties. These were achieved with both structural modification and formulation change. Toxicity of acetaminophen is related to its metabolism. Major side effect of NSAID is the GI toxicity. Some are designed as prodrugs to reduce this side effect. selective NSAID has significantly reduced GI toxicity