Theory of thermal Dosage ■ Drug Dose during Chemotherapy (AUC) - Design treatment plan Predict treatment results Dose determination during tumor thermal treatment -Various treating protocols Different temperatures Heating rate different duration Different treatment frequency and number of multiple fractions,et.al. -Relative biological effect(protein inactivation,DNA damage,apoptosis, immunological response,HSP,others)-cell survival rateTheory of thermal Dosage Drug Dose during Chemotherapy (AUC) – Design treatment plan – Predict treatment results Dose determination during tumor thermal treatment –Various treating protocols Different temperatures Heating rate different duration Different treatment frequency and number of multiple fractions, et.al. –Relative biological effect (protein inactivation, DNA damage, apoptosis, immunological response, HSP, others) ‐cell survival rate