Classification of Natural Products Nonribosomal polypeptides Peptidelike compounds Biosynthesized from amino acids by a multifunctional enzyme complex without direct RNA transcription,such as penicillins Enzyme cofactors Coenzymes such as pyridoxal phosphate(PLP) Nonribosomal polypeptides ▪ Peptidelike compounds ▪ Biosynthesized from amino acids by a multifunctional enzyme complex without direct RNA transcription, such as penicillins Enzyme cofactors ▪ Coenzymes such as pyridoxal phosphate (PLP) Classification of Natural Products