Physiology Defense Defense Mechanisms and Immunology alveolar clearance(alveolar macrophages PMN, T cell) lmmunology(lgA、lgM、gG) Too strong stimuli and weak defense results in lesion and injury of the lung Asthma COPD ALI infection 复旦大学附属中山医院 呼吸科暨呼吸病研究所 上海市重点学• Defense Mechanisms and Immunology – alveolar clearance (alveolar macrophages, PMN, T cell) – Immunology (IgA、IgM、IgG) Too strong stimuli and weak defense results in lesion and injury of the lung – Asthma – COPD – ALI – infection Physiology & Defense