Physiology Defense Defense Mechanisms and Immunology physical barrier: against airbone pathogens and irritants(cough clearance, mucus cytoplasmic cilia) SIZE (diameter) HOST DEFENSES Turbinates AMBIENT AIR 10 ANATOMIC BARRIE ANGULATION OR AIR MICRO-ORGANISMS MUCO-CILIARY Turbulent flow COUGH Airway angulation AIR EXCHANGE SURFACE 05-3p SURFACTANT SONINS-IgG. FIBRONECTIN COMPLEMENT alternate pathway) ALVEOLAR MACROPHAGES 0.5 (stays in gaseous PLASMA COMPONENTS VASO-ACTIVE MEDIATORS大学附属中山医院 科暨呼吸病研究所 上海市重点学• Defense Mechanisms and Immunology – physical barrier: against airbone pathogens and irritants (cough clearance, mucus￾cytoplasmic cilia) Physiology & Defense