D.危险度特征分析 9.化学物质对人群的安全性是D A.绝对的、理论意义上的安全 B.绝对的、实用意义上的安全 C.相对的、理论意义上的安全 D.相对的、实用意义上的安全 10.一般来说，对于一种新产品投产上市之前，必须进行C A.毒理学安全性评价全程试验 B.毒理学安全性评价第一、二阶段试验 C.毒理学安全性评价第一、二、三阶段试验 D.急性毒性、亚慢性毒性、慢性毒性试验 11.A properly executed assessment of risk considers all the following EXCEPTD_ A.evaluation of data from human exposures. B.evaluation of data from laboratory animal studies C.evaluation of public perception of risks versus benefits D.evaluation of data regarding chemical production 12.A virtually safe dose may be defined as a A.the dose that has an associated risk of carcinogenicity of 1 in 100,000. B.the dose to which an individual may be exposed daily with statistical assurance that cancer will not develop C.an extrapolation from all available data that provides a level of exposure that will not induce harm in workers D.the dose at which an effect was not observed. 三、简答题 1.简述毒理学安全性评价的主要内容。 答案要点：第一阶段为急性毒性试验和局部毒性试验：第二阶段为遗传毒性实验 和致畸试验：第三阶段包括亚慢性毒性试验、生殖试验和代谢试验；第四阶段包 括慢性毒性试验和致癌试验。 2.简述危险性分析的步骤和内容D．危险度特征分析 9. 化学物质对人群的安全性是 D A．绝对的、理论意义上的安全 B．绝对的、实用意义上的安全 C．相对的、理论意义上的安全 D．相对的、实用意义上的安全 10. 一般来说，对于一种新产品投产上市之前，必须进行 C A．毒理学安全性评价全程试验 B．毒理学安全性评价第一、二阶段试验 C．毒理学安全性评价第一、二、三阶段试验 D．急性毒性、亚慢性毒性、慢性毒性试验 11. A properly executed assessment of risk considers all the following EXCEPT D A. evaluation of data from human exposures. B. evaluation of data from laboratory animal studies. C. evaluation of public perception of risks versus benefits. D. evaluation of data regarding chemical production. 12. A virtually safe dose may be defined as A A. the dose that has an associated risk of carcinogenicity of 1 in 100,000. B. the dose to which an individual may be exposed daily with statistical assurance that cancer will not develop. C. an extrapolation from all available data that provides a level of exposure that will not induce harm in workers. D. the dose at which an effect was not observed. 三、简答题 1. 简述毒理学安全性评价的主要内容。 答案要点：第一阶段为急性毒性试验和局部毒性试验；第二阶段为遗传毒性实验 和致畸试验；第三阶段包括亚慢性毒性试验、生殖试验和代谢试验；第四阶段包 括慢性毒性试验和致癌试验。 2. 简述危险性分析的步骤和内容