verity of elene and Taeimooy of 与有机酸的酯化: ROH RCOOH- R COOR H,O 3脱水——消除反应 1)分子内脱水:CH3CH2OH CH2=CH 190°C 反应活性:3°>2°>1°(太多为E历程,因为H2O+易离去) 消去的取向:(查依采夫规则) CH3 CH2-CH-CH H2SOA CH3 CH=CHCH3 CH3=CH 86°C oH 80% 20% 也有重排(E1历程) CH H3 CH CH3-C-CH--CH3 CHECH CHOH H3C CH 70% 30% rganicUniversity of Science and Technology of China Organic Chem 与有机酸的酯化： ROH + R'COOH R'COOR + H2O 3.脱水——消除反应 1).分子内脱水： CH3CH2OH CH2 CH2 H2 SO4 190C 反应活性：3º> 2º> 1º(太多为E1历程，因为H2O+易离去) 消去的取向：(查依采夫规则) CH3CH2 CH OH CH3 H2 SO4 86C CH3CH CHCH3 + CH3CH2CH CH2 80% 20% 也有重排（E1历程） CH3 C CH3 CH3 CH OH CH3 C C H3C H3C CH3 CH3 H + CH3 C CH3 CH3 + CH CH2 70% 30%