MELAMINE-CONTAMINATED POWDERED FORMULA AND UROLITHIASIS ed by a grant from the National Key Technology Re- e relied on reported alues ofthe melamine content In conclusion,we suggest that children with urinary stones induced by melamine-tainted for- mula require careful ongoing and long-term fol- ow-up REFERENCES c the UK. Sun N.Shen Y.Sun Q,ct al.Melamine sign up thre 1074 N ENGLJ MED 360:11 NEJM.ORG MARCH 12,2006 ngland Joumal of Medicin1074 n engl j med 360;11 nejm.org march 12, 2009 Melamine-Contaminated Powdered Formula and Urolithiasis melamine concentration of milk formulas our￾selves; instead, we relied on reported values of the melamine content. In conclusion, we suggest that children with urinary stones induced by melamine-tainted for￾mula require careful ongoing and long-term fol￾low-up. Supported by a grant from the National Key Technology Re￾search and Development Program of China. No potential conflict of interest relevant to this article was reported. We thank all the doctors, nurses, and other staff members of the Departments of Pediatrics, Ultrasonic Medicine, and Laboratory Medicine of Peking University First Hospital who kindly provided their cooperation in this study, and the gradu￾ate students of Peking University First Hospital who provided assistance in data management. References 1. Thompson ME, Lewin-Smith MR, Ka￾lasinsky VF, et al. Characterization of melamine-containing and calcium oxalate crystals in three dogs with suspected pet food-induced nephrotoxicosis. Vet Pathol 2008;45:417-26. 2. Chertow GM, Milford EL, Mackenzie HS, Brenner BM. Antigen-independent de￾terminants of cadaveric kidney transplant failure. JAMA 1996;276:1732-6. 3. Coward RJ, Peters CJ, Duffy PG, et al. Epidemiology of paediatric renal stone dis￾ease in the UK. Arch Dis Child 2003;88: 962-5. [Erratum, Arch Dis Child 2004;89: 797.] 4. Sun N, Shen Y, Sun Q, et al. Melamine related urinary calculus and acute renal failure in infants. Zhonghua Er Ke Za Zhi 2008;46:810-5. (In Chinese.) 5. Gilsanz V, Fernal W, Reid BS, Stanley P, Ramos A. Nephrolithiasis in premature infants. Radiology 1985;154:107-10. Copyright © 2009 Massachusetts Medical Society. receive immediate notification when a journal article is released early To be notified when an article is released early on the Web and to receive the table of contents of the Journal by e-mail every Wednesday evening, sign up through our Web site at NEJM.org. The New England Journal of Medicine Downloaded from nejm.org on October 18, 2011. For personal use only. No other uses without permission. Copyright © 2009 Massachusetts Medical Society. All rights reserved