3.2Ti(Opri)2(N32的选择性开环 N OH Ti(oPr)2(N3) OH R OH R OH OH R Condition C-3/C-2 Y% Et NaN3/NH4CI, 7h 5.8:1 95 TOPr)N3)2,0.08h 36:1 8 PhCH2 NaN3/NH4CL, 3.5h 1.4:1 71 TOPr)N3)2,0.16h 27:1 96 C-Hex NaN3/NH4Cl, 10h 1.7:1 TOPr)N3)2,0.25h 20:1 94 t-Bu NaN3/NH4CL, 12h 1:100 47 Ti(OPri(N3)2, 0.75h 2:1 96 NaN3/NH4CL, 2.7h 100:1 100 TOPT)(N32,0.08h100:1 763.2 Ti(Opri)2 (N3 )2的选择性开环 Ti(OPr i ) 2 (N3 ) 2 -------------------------------------------------------------------------- R Condition C-3/C-2 Y% -------------------------------------------------------------------------- Et NaN3 /NH4 Cl, 7h 5.8:1 95 Ti(OPri)(N3 ) 2 , 0.08h 36:1 88 PhCH2 NaN3 /NH4 Cl, 3.5h 1.4:1 71 Ti(OPri)(N3 ) 2 , 0.16h 27:1 96 C-Hex. NaN3 /NH4 Cl, 10h 1.7:1 93 Ti(OPri)(N3 ) 2 , 0.25h 20:1 94 t-Bu NaN3 /NH4 Cl, 12h 1:100 47 Ti(OPri)(N3 ) 2 , 0.75h 2:1 96 Ph NaN3 /NH4 Cl, 2.7h 100:1 100 Ti(OPri)(N3 ) 2 , 0.08h 100:1 76 -------------------------------------------------------------------------- R OH O R OH OH N3 R OH OH N3