亲核取代反应 Nucleophilic Substitution Reaction 实验事实 TSCI CH3COO HO-H Pyridine H OTS AcOH al=+33.0 a]=+31 al=-7.06 H,O OH H20 OH CHCOO TsCI H OAC TsO H Pyridine H-O H a=+7.060 a]=-33.0 a]=-33.亲核取代反应 Nucleophilic Substitution Reaction 实验事实 H O-H TsCl Pyridine H OTs [ a ] = +33.0 0 [ a ] = +31.1 0 AcO H [ a ] = - 7.06 0 H OAc [ a ] = + 7.06 0 H-O H [ a ] = - 33.0 0 CH3COO - H2O OH - TsO H [ a ] = - 33.0 0 Pyridine TsCl CH3COO - H2O OH -