Encephalitis B Jap Pathology Gray matter involved, mainly Cerebral CorteX--BG Thalamus Gross Ins pection: Congestion of Meninges Brain Edema Microscopic findings: Sieve-like softening foci, well demarcated Necrosis of neurous with foamy cell formation Congestion and perivascular cuffing Proliferation of glial cells Microglia proliferation(acute stage) Astrocyte proliferation(chronic stage)Encephalitis B Jap. Pathology  Gray matter involved, mainly Cerebral Cortex—B.G. Thalamus  Gross Inspection: Congestion of Meninges Brain Edema  Microscopic findings: Sieve-like softening foci, well demarcated Necrosis of neurous with foamy cell formation Congestion and perivascular cuffing Proliferation of glial cells Microglia proliferation(acute stage) Astrocyte proliferation(chronic stage)