An Overview of Metabolism and Biochemical Energy Imagine that the product n can react with substance o to yield p and q in a second,strongly favorable reaction that has a large equilibrium constant and△G<<0: (2)n+0p+9△G<0 Because the two reactions are coupled through n,the transformation of A to B becomes possible When an amount of n is formed in reaction 1,it undergoes a complete conversion in reaction 2,thereby removing it from the first equilibrium and forcing reaction 1 to continually replenish n until the reactant A is gone The two reactions added together have a favorable AG <0 The favorable reaction 2"drives"the unfavorable reaction 1 (1)A+m←→B+H △G>0 (2)H+0一→p+q △G<<0 Net:A+m+0-→B+p+q △G<0 企Laeri'g月haImagine that the product n can react with substance o to yield p and q in a second, strongly favorable reaction that has a large equilibrium constant and ∆G << 0: (2) n + o p + q ∆G << 0 Because the two reactions are coupled through n, the transformation of A to B becomes possible ▪ When an amount of n is formed in reaction 1, it undergoes a complete conversion in reaction 2, thereby removing it from the first equilibrium and forcing reaction 1 to continually replenish n until the reactant A is gone ▪ The two reactions added together have a favorable ∆G < 0 ▪ The favorable reaction 2 “drives” the unfavorable reaction 1 An Overview of Metabolism and Biochemical Energy