977779 4688 Phospholipase A2+ Injury or other stimulus Arachidonic acid Cyclooxygenase 5-Lipoxygenase (COX) Prostaglandin G2 5-HPETE Prostaglandin H2 Leukotriene A4 Prostaglandin 12 Prostaglandin E2 Thromboxane A2 Leukotriene B4 Leukotriene Ca Prostaglandin F2 Leukotriene D4 Leukotriene E 贝前列素Beraprost Beraprost is a synthetic analogue of prostacyclin.under clinical trials for the treatment of pulmonary hypertension.It is also being studied for use in avoiding reperfusion injury. As an analogue of prostacyclin PG12,beraprost effects vasodilation,which in turn lowers the blood pressure.Beraprost also inhibits platelet aggregation,though the role this phenomenon may play in relation to pulmonary hypertension has yet to be determined.贝前列素 Beraprost As an analogue of prostacyclin PGI2, beraprost effects vasodilation, which in turn lowers the blood pressure. Beraprost also inhibits platelet aggregation, though the role this phenomenon may play in relation to pulmonary hypertension has yet to be determined. Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury