Tetrahydrofolate(transfer of C units) NHCHCH2CH2C- S-Adenosylmethionine(methyl transfer) CH3 -OCCHCH2CH2-S-CH2 +NH3 Lipoic acid(acyl transfer) CH2OPO32- CH2CH2CH2CH2CO2- CHO HnN人o CHa Biotin (carboxylation HNN一H S-Adenosylmethionine (methyl transfer) Lipoic acid (acyl transfer) Thiamin diphosphate (decarboxylation) Pyridoxal phosphate (amino acid metabolism) Tetrahydrofolate (transfer of C1 units) CH2 –OCCHCH2CH2 CH2CH2CH2CH2CO2 – S + +NH3 O CH3 O OHOH H2N N N N N H N H H O O H H NHCHCH2CH2C O– 1–5 CO2 O – S S CH2OPO3 2– CH3 CHO OH N H + H CH3 –OPOPOCH2CH2 N + S NH2 CH3 N N O O– O O– Biotin (carboxylation) N N H H O S H H H CH2CH2CH2CH2CO2 – NH2 N N N N Unless otherwise noted, all content on this page is © Cengage Learning. 42912_33_EP2-EP3.indd 3 1/10/14 1:21 PM Copyright 2015 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it