manifestations a Most infections asymptomatic, 95% a Abortive polio(minor illness), 5%: fever, malaise, sore throat myalgia, headache) a Aseptic meningitis(non paralytic polio),1% Paralytic polio(major illness),0.1%: asymetric flaccid paralysis/ paresis. Lower, or upper extremities, thoracic, abdominal, bulbar Involvement: spinal cord anterior horn cells, motor cortex, dorsal root ganglia neurologic sequela(2 /3) Post-polio syndrome: progressive atrophy years latermanifestations ◼ Most infections asymptomatic, 95% ◼ Abortive polio (minor illness), 5%: fever, malaise, sore throat, myalgia, headache) ◼ Aseptic meningitis (non paralytic polio), 1% ◼ Paralytic polio (major illness), 0.1%: asymetric flaccid paralysis / paresis. Lower, or upper extremities, thoracic, abdominal, bulbar. Involvement : spinal cord anterior horn cells, motor cortex, dorsal root ganglia neurologic sequela (2/3) ◼ Post-polio syndrome: progressive atrophy years later