甲状腺危象(thyrotoxic crisis) Treatment goal:disrupt adrenergically-mediated thyroid hormone action and inhibit further hormone synthesis and release 1.Treat precipitating cause治疗原发病 2.Inhibits synthesis of hormones from thyroid gland抑制TH合成： PTU:It also can Inhibits synthesis of more T3 from T4 at peripheral tissues Frist:600mg,then 200-300mg,Q6h 3.Inhibits release of hormones from thyroid gland抑制TH释放： Saturated solution of potassium iodide (SSKI)or sodium iodide: ·服PTU后1~2h再加用复方碘溶液，5滴，q8h,3-7天 ·或碘化钠静脉点滴，碘过敏者用碳酸锂0.5~1.5g/d 4.Beta-blocker therapy Propranolol 60~80mg Q6~8h1. Treat precipitating cause 治疗原发病 2. Inhibits synthesis of hormones from thyroid gland 抑制TH合成： • PTU：It also can Inhibits synthesis of more T3 from T4 at peripheral tissues • Frist：600mg，then 200-300mg，Q6h 3. Inhibits release of hormones from thyroid gland 抑制TH释放: • Saturated solution of potassium iodide (SSKI) or sodium iodide: • 服PTU后1～2h再加用复方碘溶液，5滴，q8h,3-7天 • 或碘化钠静脉点滴, 碘过敏者用碳酸锂 0.5~1.5g/d 4. Beta-blocker therapy • Propranolol 60~80mg Q6~8h 甲状腺危象(thyrotoxic crisis) Treatment goal: disrupt adrenergically-mediated thyroid hormone action and inhibit further hormone synthesis and release