Fudan University Cancer Center Metastatic cancer is responsible for about 90% of cancer mortality. understanding how cells disseminate from the primary tumor to invade and successfully colonize distant tissues represents the least understood and the most deadly area of cancer biology 复旦大学上海医学院肿瘤学系复旦大学上海医学院肿瘤学系 Fudan University Cancer Center Metastatic cancer is responsible for about 90% of cancer mortality. -understanding how cells disseminate from the primary tumor to invade and successfully colonize distant tissues represents the LEAST understood and the most deadly area of cancer biology