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中国中西医结合影像学杂志2015年4月第13卷第2期 119 SPACE序列定量分析交通性脑积水 脑室分流前后脑脊液体积 邹金梅,张礼荣,张建 (江苏大学附属医院影像科,江苏镇江212000) [摘要]目的:采用MRI不同翻转角脉冲触发三维扰相自旋回波( SPACE)序列测定交通性脑积水患者颅内脑脊液体积。方 法:选取30例交通性脑积水患者,男女各15例,脑室分流前及分流后分别于3.0TMR上采用 SPACE序列形成颅内与脑室的 ⅤR影像。通过软件测量获得颅内脑脊液总体积与脑室脑脊液的体积,并计算蛛网膜下腔脑脊液的体积。结果:交通性脑积水患 者脑室-腹腔(V-P)分流前颅内脑脊液总体积、脑室及蛛网膜下腔脑脊液体积均值分别为(5776±1123)cm3、(213.0±530)cm3 (364.6±88.5)cm3,分流后分别为(444.8±80.3)cm3、(1566±459)cm3、(2766±674)cm3。分流前后颅内脑脊液总体积、脑室及蛛 网膜下腔脑脊液体积差异均有统计学意义(Ⅸ0.05)。男性患者分流前后2次测量的颅内脑脊液总体积、脑室及蛛网膜下腔脑脊液 体积与女性患者相比差异均无统计学意义(P0.05)。结论: SPACE序列定量分析脑脊液含量可指导临床VP术的选择,并为准确 评价VP分流术的疗效提供客观标准。 [关键词]脑积水;磁共振成像 Study of CSF volume of communicating hydrocephalus before and after VP surgery by SPACE sequence at MRI ZOU Jinmei, ZHANG Lirong, ZHANG Jian. Department of Imaging, the Affiliated Hospital of Jiangsu University, Zhenjiang, 212001, Chi- [Abstract] Objective: To study the imaging of intracranial cerebrospinal fluid (CSF) spaces of communicating hydrocephalus using of three-dimensional turbo spin echo with variable flip angle distribution SPACE sequence before and after ventriculo"peri- toneal shunt(VP). Methods: 30 patients with communicating hydrocephalus were included in the study, volumes of total intracra- nial and ventricular CSF were obtained via the SPACE sequence at 3.0 T MRI. The CSF volumes of the total intracranial, ven- tricular and subarachnoid spaces were calculated. Results: The CSF volumes of total intracranial, ventricular and subarachnoid CSF were (577.6+ 112. )em, (213.0+530)cm, (364.6*88.5)cm,, respectively, for communicating hydrocephalus before VP. Vol- umes of those were(444.8+80.3)em, (156.6+45.9)cm, (2766+67.4)em, respectively after VP. There were significant differ- ences on CSF volumes of intracranial, ventricular and subarachnoid between pre-operation and postoperation (P 0.05). And there were no differences on volumes of men and women. Conclusions: CSF could be measured quantitatively via SPACE sequence. And it has directive significance in treatment of communicating hydrocephalus by VP operation. Key words] Hydrocephalus; Magnetic resonance imaging 交通性脑积水指脑脊液循环过程中阻塞部位在床诊断和治疗提供帮助。 脑室系统以外、蛛网膜下腔或脑脊液吸收的终点即蛛 网膜颗粒处障碍,常见于脑部外伤、脑血管病变出血、 1资料与方法 颅内感染、术后导致蛛网膜下腔粘连造成的脑积水。1.1一般资料收集我院2011年1月至2013年1 对于交通性脑积水的量的分析一直是临床医师想要月30例交通性脑积水患者,分成男女2组,每组各 解决的问题。本研究采用MRI不同翻转角脉冲触发15例;男性年龄19~58岁,平均(38.0±3.62)岁,女 三维扰相自旋回波序列( sampling perfection with ap-性年龄25~56岁,平均(403±402)岁。其中15例 plication -optimized contrasts by using different flip有外伤史,8例有颅内感染史,7例为蛛网膜下腔出 angle evolutions, SPACE)测定交通性脑积水患者行血后引起的慢性脑积水。临床表现:头痛、呕吐、视物 脑室-腹腔(Ⅴ-P)分流术前后脑脊液体积,以期为临模糊等颅内压增高表现,共济失调、记忆力下降,E- vans指数(指双侧脑室额角最大宽度与同层面内板 DOI:10.3969jisn.1672-0512.2015.02.001 最大内径之比)≥0.30。头颅MRI均示第三、四脑室 [基金项目]江苏大学医学临床科技发展基金项目(LY201201 及侧脑室扩大,并排除梗阻性脑积水 [通信作者]邹金梅, E-mail: zoujinmeil23@126coma 1.2仪器与方法采用 Siemens trio-Tim超导型中国中西医结合影像学杂志 2015 年 4 月第 13 卷第 2 期 论 著 交通性脑积水指脑脊液循环过程中阻塞部位在 脑室系统以外、蛛网膜下腔或脑脊液吸收的终点即蛛 网膜颗粒处障碍,常见于脑部外伤、脑血管病变出血、 颅内感染、术后导致蛛网膜下腔粘连造成的脑积水。 对于交通性脑积水的量的分析一直是临床医师想要 解决的问题。 本研究采用 MRI 不同翻转角脉冲触发 三维扰相自旋回波序列(sampling perfection with ap￾plication -optimized contrasts by using different flip angle evolutions,SPACE)[1] 测定交通性脑积水患者行 脑室-腹腔(V-P)分流术前后脑脊液体积,以期为临 床诊断和治疗提供帮助。 1 资料与方法 1.1 一般资料 收集我院 2011 年 1 月至 2013 年 1 月 30 例交通性脑积水患者,分成男女 2 组,每组各 15 例;男性年龄 19~58 岁,平均(38.0±3.62)岁,女 性年龄 25~56 岁,平均(40.3±4.02)岁。 其中 15 例 有外伤史,8 例有颅内感染史,7 例为蛛网膜下腔出 血后引起的慢性脑积水。 临床表现:头痛、呕吐、视物 模糊等颅内压增高表现,共济失调、记忆力下降,E￾vans 指数(指双侧脑室额角最大宽度与同层面内板 最大内径之比)≥0.30。 头颅 MRI 均示第三、四脑室 及侧脑室扩大,并排除梗阻性脑积水。 1.2 仪器 与 方 法 采 用 Siemens Trio-Tim 超导 型 DOI:10.3969/j.issn.1672—0512.2015.02.001 [基金项目] 江苏大学医学临床科技发展基金项目(JLY201201 67)。 [通信作者] 邹金梅,E—mail:zoujinmei123@126.com。 SPACE 序列定量分析交通性脑积水 脑室分流前后脑脊液体积 邹金梅,张礼荣,张 建 (江苏大学附属医院影像科,江苏 镇江 212000) [摘要] 目的:采用 MRI 不同翻转角脉冲触发三维扰相自旋回波(SPACE)序列测定交通性脑积水患者颅内脑脊液体积。 方 法:选取 30 例交通性脑积水患者,男女各 15 例,脑室分流前及分流后分别于 3.0 T MRI 上采用 SPACE 序列形成颅内与脑室的 VR 影像。 通过软件测量获得颅内脑脊液总体积与脑室脑脊液的体积,并计算蛛网膜下腔脑脊液的体积。 结果:交通性脑积水患 者脑室 - 腹腔(V-P)分流前颅内脑脊液总体积、脑室及蛛网膜下腔脑脊液体积均值分别为(577.6±112.3)cm3 、(213.0±53.0)cm3 、 (364.6±88.5)cm3 ,分流后分别为(444.8±80.3)cm3 、(156.6±45.9)cm3 、(276.6±67.4)cm3 。 分流前后颅内脑脊液总体积、脑室及蛛 网膜下腔脑脊液体积差异均有统计学意义(P< 0.05)。 男性患者分流前后 2 次测量的颅内脑脊液总体积、脑室及蛛网膜下腔脑脊液 体积与女性患者相比差异均无统计学意义(P> 0.05)。 结论:SPACE 序列定量分析脑脊液含量可指导临床 V-P 术的选择,并为准确 评价 V-P 分流术的疗效提供客观标准。 [关键词] 脑积水;磁共振成像 Study of CSF volume of communicating hydrocephalus before and after VP surgery by SPACE sequence at MRI ZOU Jinmei,ZHANG Lirong,ZHANG Jian. Department of Imaging,the Affiliated Hospital of Jiangsu University,Zhenjiang,212001,Chi￾na. [Abstract] Objective:To study the imaging of intracranial cerebrospinal fluid (CSF) spaces of communicating hydrocephalus using of three-dimensional turbo spin echo with variable flip-angle distribution SPACE sequence before and after ventriculo-peri￾toneal shunt (VP). Methods:30 patients with communicating hydrocephalus were included in the study,volumes of total intracra￾nial and ventricular CSF were obtained via the SPACE sequence at 3.0 T MRI. The CSF volumes of the total intracranial,ven￾tricular and subarachnoid spaces were calculated. Results:The CSF volumes of total intracranial,ventricular and subarachnoid CSF were (577.6±112.3)cm3 ,(213.0±53.0)cm3 ,(364.6±88.5)cm3 ,respectively,for communicating hydrocephalus before VP. Vol￾umes of those were (444.8±80.3)cm3 ,(156.6±45.9)cm3 ,(276.6±67.4)cm3 ,respectively after VP. There were significant differ￾ences on CSF volumes of intracranial,ventricular and subarachnoid between pre-operation and postoperation (P< 0.05). And there were no differences on volumes of men and women. Conclusions:CSF could be measured quantitatively via SPACE sequence. And it has directive significance in treatment of communicating hydrocephalus by VP operation. [Key words] Hydrocephalus;Magnetic resonance imaging ·119·
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