BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 Cells can be entrapped with high lability 4. 8. UV lamp Collagen 3 gAG %ww)0.2 (W ww liquid H山 ⊥LL 810121416 lel Figure 3. Biochemical analysis. Evolution of GAG and total collagen contents (%o wet weight) over 14 days of photon- capsulated bovine chondrocytes Example Biomedical Hydrogel Materials Formed from hydrophilic biocompatible polymers, often polymers that can be safely eliminated by the body if the breaks down medicine CH 小(tk内c[G wl(ethylene lysol) monomethyl ether[PEGME) R Contact Lenses General methacrylates PHEMAlpolyfetby lene temphhalateIPTPEI Artifcial Tendons Membranes for plasmapheresis HEMA-b-aloxane) xual epan reconstraction PVA poly(ar b acid [PAAL, poly Ophthal appliation PA HEMA MMA Articular Cartilage Cantreard Drug Deliery Poly(glycolic aod)[ HGAL Poly( lacte arid (PLAL TAHL. 1 IComtieundH polycyanoucn, fumane acid- PEGi, seba acid 1,3-bopcarboxypbraaxyl propane[P(CFP-SA) Complexing hydrogels ALAA-g-EGL polYacrylic acid-grafted-pol PHEMA, P\A PNVE polylethylene-oa-vinyl acetate) ly(- isopropyl ary lami)IPNIPAAm mperalun-sensatIve PAAl Poly (actic acid [PAAl PNIPAAm PAA. PNPAAPALAA dniy甲中 bn tud tm t endk naan dd wed than Lecture 7-Hydrogels 1 9of15BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 • Cells can be entrapped with high viability4,8: UV lamp liquid gel Example Biomedical Hydrogel Materials6 Formed from hydrophilic biocompatible polymers, often polymers that can be safely eliminated by the body if the gel breaks down. CH3 CH=C C=O O R General methacrylates Lecture 7 – Hydrogels 1 9 of 15