Functions of the Extracellular Matrix Mechanical support for cell anchorage and cell migration, and maintenance of cell polarity o Control of cell proliferation Scaffolding for tissue renewal Establishment of tissue microenvironmentsFunctions of the Extracellular Matrix  Mechanical support for cell anchorage and cell migration, and maintenance of cell polarity  Control of cell proliferation  Scaffolding for tissue renewal  Establishment of tissue microenvironments