Epithelium Integrins Fibroblast BASEMENT MEMBRANE Integrins Type IV collagen Endothelial cells ◆Laminin Adhesive Proteoglycan glycoproteins Capillary 瓶欢 -Int egrins 孩封 Fibroblast Pr oteoglycan INTERSTITIAL MATRIX ·Fibrillar collagens Type IV collagen- ·Elastin -Cross-linked Proteoglycan and Laminin- Proteoglycan collagen triple helices hyaluronan The major components of the extracellular matrix(ECM) The major components of the extracellular matrix (ECM)