Science www.sciencemag.org/cgi/content/full/science.aad1329/dci NAAAS Supplementary Materials for Anticancer immunotherapy by Ctla-4 blockade relies on the gut microbiota Marie Vetizou, Jonathan M. Pitt, Romain Daillere, Patricia Lepage, Nadine Waldschmitt Caroline Flament, Sylvie Rusakiewicz, Bertrand Routy, Maria P. Roberti, Connie P. M Duong, Vichnou Poirier-Colame, Antoine Roux, Sonia Becharef, Silvia Formenti, Encouse Golden, Sascha Cording, Gerard Eberl, Andreas Schlitzer, Florent Ginhoux Sridhar Mani, Takahiro Yamazaki, Nicolas Jacquelot, David P. Enot, Marion Berard Jerome Nigou, Paule Opolon, Alexander Eggermont, Paul-Louis Woerther, Elisabeth Chachaty, Nathalie Chaput, Caroline Robert, Christina Mateus, Guido Kroemer, Didier Raoult, Ivo Gomperts Boneca, Franck Carbonnel, Mathias Chamaillard Laurence zitvogel *Corresponding author. E-mail: laurence. zitvogel@gustaveroussyfr Published 5 November 2015 on Science Express DOI: 10.1 126/science. aad 1329 This pdf file includes Materials and method nceswww.sciencemag.org/cgi/content/full/science.aad1329/DC1 Supplementary Materials for Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota Marie Vétizou, Jonathan M. Pitt, Romain Daillère, Patricia Lepage, Nadine Waldschmitt, Caroline Flament, Sylvie Rusakiewicz, Bertrand Routy, Maria P. Roberti, Connie P. M. Duong, Vichnou Poirier-Colame, Antoine Roux, Sonia Becharef, Silvia Formenti, Encouse Golden, Sascha Cording, Gerard Eberl, Andreas Schlitzer, Florent Ginhoux, Sridhar Mani, Takahiro Yamazaki, Nicolas Jacquelot, David P. Enot, Marion Bérard, Jérôme Nigou, Paule Opolon, Alexander Eggermont, Paul-Louis Woerther, Elisabeth Chachaty, Nathalie Chaput, Caroline Robert, Christina Mateus, Guido Kroemer, Didier Raoult, Ivo Gomperts Boneca, Franck Carbonnel, Mathias Chamaillard, Laurence Zitvogel* *Corresponding author. E-mail: laurence.zitvogel@gustaveroussy.fr Published 5 November 2015 on Science Express DOI: 10.1126/science.aad1329 This PDF file includes Materials and Methods Figs. S1 to S22 Tables S1 to S5 References