Local signs and general reaction Local signs 尺 edness(rbor) Heat (calor)----m-hyperemia Swelling(tumor)-------hyperemia and edema Pain(dolor)-----nerve ending irritated by exudates and inflammatory mediators DysfunctionLocal signs and general reaction Local signs: Redness (rubor) Heat (calor)------hyperemia Swelling (tumor)-------hyperemia and edema Pain (dolor)-----nerve ending irritated by exudates and inflammatory mediators. Dysfunction