OUTLINE 1 Definition 2 Causes 3 Basic pathological changes 4 Local signs and general reaction 5 Histological types 6 Inflammatory mediator and chemotaxis 7 Sequels
OUTLINE 1 Definition 2 Causes 3 Basic pathological changes 4 Local signs and general reaction 5 Histological types 6 Inflammatory mediator and chemotaxis 7 Sequels
INFLAMMATION Definition Inflammation is a dynamic processes by which livin tissue reacts to injury. They concern vascular and connective tissue particularly
Definition Inflammation is a dynamic processes by which living tissue reacts to injury. They concern vascular and connective tissue particularly. INFLAMMATION
Local signs and general reaction Local signs 尺 edness(rbor) Heat (calor)----m-hyperemia Swelling(tumor)-------hyperemia and edema Pain(dolor)-----nerve ending irritated by exudates and inflammatory mediators Dysfunction
Local signs and general reaction Local signs: Redness (rubor) Heat (calor)------hyperemia Swelling (tumor)-------hyperemia and edema Pain (dolor)-----nerve ending irritated by exudates and inflammatory mediators. Dysfunction
General reaction (1)Fever % (2)Increased leukocyte count
General reaction: (1) Fever (2) Increased leukocyte count
(2)-----releasing leukocytes from bone marrow by IL-1 and TNF immature neutrophils(rod nucleus) increased in peripheral blood(left divert) Depending on the duration inflammation is divided into acute and chronic inflammation
(2) ------releasing leukocytes from bone marrow by IL-1 and TNF, immature neutrophils (rod nucleus) increased in peripheral blood (left divert). Depending on the duration , inflammation is divided into acute and chronic inflammation
2 Causes Physical agents: mechanical trauma: over heat or cold ultra-violet or ionising radiatio门 Chemical substances: simple chemicals eg acids, alkaline and organic poisons, toxins from various bacteria
2 Causes Physical agents: mechanical trauma; over heat or cold; ultra-violet or ionising radiation. Chemical substances: simple chemicals eg. acids, alkaline and organic poisons, toxins from various bacteria