A.General Pharmacological properties 2. Antipyretic effects Inhibition of pce 2 production in the hypothalamus induced by endogenous pyregens after pathological stimuli -y temperature↓ notes: symptomatic control only, not be indicated in all patients with fever The effect on body temperature is different from that of chlorpromazine 大亭院2.Antipyretic effects Inhibition of PGE2 production in the hypothalamus induced by endogenous pyregens after pathological stimuli → temperature  notes: symptomatic control only, not be indicated in all patients with fever. The effect on body temperature is different from that of chlorpromazine. A. General Pharmacological properties