Stimulus Disturbance of cell membranes Phospholipids Phospholipase inhibitors Corticosteroids Phospholipase Fatty acid substitution(diet) Arachidonic acid Lipoxygenase inhibitors Lipoxygenase Cyclooxygenase NSAID. ASA Leukotrienes eceptor antagonists LTBA LTC//DA/E4 ( Prostaglandins Thromboxane Prostacyclin Phagocyte Alteration of vascula permeability, bronchial activation constriction, increased Leukocyte modulation secretion Colchicine Inflammatio Bronchospasm Inflammation congestion, mucous plugging I