1/26/2016 Capsule Klebsiella pneumoniae Cell Wall Components Glycocalyx around the cell wall o0 M protein ·Increases virulence Streptococcus pyogenes Impairs phagocytosis g found on cell surface and fimbriae Streptococcus pneumoniae- pneumonia mediates attachment to -Haemophilus influenzae-pneumonia epithelial cells and meningitis -helps bacteria resist Bacillus anthracis-anthrax phagocytosis yersinia pestis-plague -Klebsiella pneumoniae -bacterial pneumonia Cell Wall Components Cel‖Wall Components Opa protein Waxy lipid(mycolic acid) -Neisseria gonorrhoeae outer membrane protein -Mycobacterium tuberculosis allows attachment to -resist digestion inside macrophages where the host cell as do it can multiply fimbriae following attachment the host cell takes up the bacteria where it resides 1/26/2016 5 Capsule • Glycocalyx around the cell wall • Increases virulence Klebsiella pneumoniae • Impairs phagocytosis – Streptococcus pneumoniae - pneumonia – Haemophilus influenzae - pneumonia and meningitis – Bacillus anthracis - anthrax – Yersinia pestis - plague – Klebsiella pneumoniae – bacterial pneumonia Cell Wall Components M protein – Streptococcus pyogenes – found on cell surface and fimbriae – mediates attachment to epithelial cells – helps bacteria resist phagocytosis Cell Wall Components Opa protein – Neisseria gonorrhoeae – outer membrane protein – allows attachment to the host cell as do fimbriae – following attachment the host cell takes up the bacteria where it resides Cell Wall Components Waxy lipid (mycolic acid) – Mycobacterium tuberculosis – resist digestion inside macrophages where it can multiply