Section I Basic Principles Introduction Total hours required- 2 Total Classes required Days of Study Mor Peri l of Study Week 1&2-First semester Lecture 1 Class I i.How to define pharmacology ii.The Nature of Drugs a.The Physical Nature of Drugs b.Drug Size c.Drug Reactivity and Drug-Receptor Bonds d.Drug Shape e.Rational Drug Design iii.Drug-Body Interaction iv. Ph armacody amic Principle a.Types of Drug-Receptor Interactions b.Agonists That Inhibit Their Binding Molecules and Partial Agonists c.Duration of Drug Action d.Receptors and Inert Binding Sites v.Pharmacokinetic Principles a.Permeation 1.Aqueous diffusion ii.Lipid diffusion ii.Special carriers iv.Endocytosis and Exocytosis b.Fick's Law of Diffusion c.Ionization of Weak Acids and Weak Bases;the Henderson-Hasselbalch Equation Drug Receptors Pharmacodynamics Total hours required= 6 Total Classes required Days of Study Tue,Wed Period of Study Week 3&4-First semester a.Lecture 1 Class IⅡ i.What is the receptor? ii.Macromolecule nature of drug recaptor Section I Basic Principles Introduction Total hours required = 2 Total Classes required = 1 Days of Study = Mon Period of Study = Week 1&2 –First semester Lecture 1 Class I i. How to define pharmacology ii. The Nature of Drugs a. The Physical Nature of Drugs b. Drug Size c. Drug Reactivity and Drug-Receptor Bonds d. Drug Shape e. Rational Drug Design iii. Drug-Body Interaction iv. Pharmacodynamic Principles a. Types of Drug-Receptor Interactions b. Agonists That Inhibit Their Binding Molecules and Partial Agonists c. Duration of Drug Action d. Receptors and Inert Binding Sites v. Pharmacokinetic Principles a. Permeation i. Aqueous diffusion ii. Lipid diffusion iii. Special carriers iv. Endocytosis and Exocytosis b. Fick’s Law of Diffusion c. Ionization of Weak Acids and Weak Bases; the Henderson-Hasselbalch Equation Drug Receptors & Pharmacodynamics Total hours required = 6 Total Classes required = 3 Days of Study = Tue, Wed Period of Study = Week 3&4 –First semester a. Lecture 1 Class II i. What is the receptor? ii. Macromolecule nature of drug recaptor