Epidemiology As a rule, uric acid levels are elevated for 20 years before the onset of gout In men, the peak age of onset of gout in men is in the four th to sixth decade of life. However, onset may occur in me n in their early 20s who have a genetic predisposition and lifestyle risk factors. In women, peak age of onset is in the sixth to eighth decade of life Tophi are typically detectable clinically approximately 10 y ears after the first gout attack Olaniyi-Leyimu BY. Consider gout in patients with risk factors, regardless of age. Am Fam Physician, Jul 15 2008, 78(2): 176 院4 浙医二院 Epidemiology As a rule, uric acid levels are elevated for 20 years before the onset of gout. In men, the peak age of onset of gout in men is in the four th to sixth decade of life. However, onset may occur in me n in their early 20s who have a genetic predisposition and lifestyle risk factors. In women, peak age of onset is in the sixth to eighth decade of life. Tophi are typically detectable clinically approximately 10 y ears after the first gout attack. Olaniyi-Leyimu BY. Consider gout in patients with risk factors, regardless of age. Am Fam Physician. Jul 15 2008;78(2):176