4 The effects of some certain anatomic features are two sides of coin e.g.,skull (the rigid confines): protects the brain from trauma and noxious elements in the external environment >renders the brain vulnerable to expansile intracranial lesions,raise intracranial pressure-compromise the function of the organ,cerebral hernia④ The effects of some certain anatomic features are two sides of coin e.g., skull (the rigid confines):  protects the brain from trauma and noxious elements in the external environment  renders the brain vulnerable to expansile intracranial lesions, raise intracranial pressure → compromise the function of the organ, cerebral hernia