Organ effects of cholinergic agonists GI -increases in tone,amplitude of contractions,and peristaltic activity of the stomach and intestines; enhances secretory activity of the gastrointestinal tract. Urinary bladder-increase ureteral peristalsis,contract the detrusor muscle of the urinary bladder,increase the maximal voluntary voiding pressure,and decrease the capacity of the bladder. 。 Other effects-Increased secretion from all glands that receive parasympatetic enervation(salivary,lacrimal, tracheobronchial,digestive and exocrine sweat glands)Organ effects of cholinergic agonists • GI - increases in tone, amplitude of contractions, and peristaltic activity of the stomach and intestines; enhances secretory activity of the gastrointestinal tract. • Urinary bladder - increase ureteral peristalsis, contract the detrusor muscle of the urinary bladder, increase the maximal voluntary voiding pressure, and decrease the capacity of the bladder. • Other effects – Increased secretion from all glands that receive parasympatetic enervation (salivary, lacrimal, tracheobronchial, digestive and exocrine sweat glands)