Fluid, Electrolyte Acid-base Disorders B. Property of dehydration Type of Serum Pathophysiology dehydration Pathogeny sodium clinical characteristic ECF: decrease Acute 130~150 Osmotic pressure Isosmotic gastrointestinal intracellular= extracellular) fluid lose mmol /L Dehydrant volume accord with dehydrant physical sign ECF: severely decrease, Chronic Hypotonic gastrointestinal <130 Easily shock fluid lose mmol/L Severer dehydrant sign than the other two kinds ICF: severely decrease, High grade 150 Hyperosmotic fever, Infection mmol /L Milder dehydrant sign than the other two kindsType of dehydration Pathogeny Serum sodium Pathophysiology & clinical characteristic Isosmotic Acute gastrointestinal fluid lose 130～150 mmol / L ECF: decrease, Osmotic pressure (intracellular = extracellular) Dehydrant volume accord with dehydrant physical sign Hypotonic Chronic gastrointestinal fluid lose <130 mmol / L ECF: severely decrease, Easily shock ， Severer dehydrant sign than the other two kinds Hyperosmotic High grade fever, Infection >150 mmol / L ICF: severely decrease, Milder dehydrant sign than the other two kinds Fluid, Electrolyte & Acid-base Disorders B. Property of dehydration