Non-synaptic chemical transmission Vesicle The postganglionic neurons innervate the ⊙ smooth muscles Smooth muscle ⊙ no recognizable endplates Intervaricose Axon segment or other postsynaptic Varicosity specializations, Mitochondrion The multiple branches are beaded with enlargements (varicosities) that are not Varicosity covered by Schwann cells and contain synaptic vesicles Terminal Fig. Ending of postganglionic autonomic neurons on smooth muscleNon-synaptic chemical transmission The postganglionic neurons innervate the smooth muscles. • No recognizable endplates or other postsynaptic specializations; • The multiple branches are beaded with enlargements (varicosities) that are not covered by Schwann cells and contain synaptic vesicles; Fig. : Ending of postganglionic autonomic neurons on smooth muscle