Non-synaptic chemical transmission continued In noradrenergic neurons, the varicosities are about ⊙ 5μm, with up to20,000 Smooth muscle varicosities per neuron ⊙o Intervaricose Axon segment Transmitter is apparently Varicosity released at each varicosity, Mitochondrion at many locations along each axon ● One neuron innervate Varicosity many effector cells 了 Termina Fig. Ending of postganglionic autonomic neurons on smooth muscle• In noradrenergic neurons, the varicosities are about 5m, with up to 20,000 varicosities per neuron; • Transmitter is apparently released at each varicosity, at many locations along each axon; • One neuron innervate many effector cells. Fig. : Ending of postganglionic autonomic neurons on smooth muscle Non-synaptic chemical transmission continued