8.3.Calculation of sterilisation time F= 又=Fk,=Frgkrd,F=Re 8.3.1.Batch sterilisation V=th=tAe ABIRT VI=AP (eIRT yit (e-AE/RT)d V=FAe -AE/RTrer Fref(e-EIRT)di ln( ) f o N N  = k F = T ref ref F k F k T  = = ( ) 1 1 R Tref T E F F e T ref − − = 8.3.1. Batch sterilisation E RT t t k tAe− /  = = t A e dt t E RT  −  = 0 / ( ) E RTref FAe− /  = dt E RT e ref F t dt E RT e t ) / ( 0 ) / ( −   −  =   8.3. Calculation of sterilisation time