Receptor-Epitope Concepts Most biological systems can be viewed in terms of interactions between receptors and epitopes (hand and glove"). Specificity of the interaction between the receptor and epitope is determined by the amino acid sequence of the receptor ("tailoring the glove"). If the glove is too big,the glove falls off. If the glove is too small,you can't get your hand into it. If the glove is missing fingers...Receptor-Epitope Concepts ◼ Most biological systems can be viewed in terms of interactions between receptors and epitopes (“hand and glove”). ◼ Specificity of the interaction between the receptor and epitope is determined by the amino acid sequence of the receptor (“tailoring the glove”). ◼ If the glove is too big, the glove falls off. ◼ If the glove is too small, you can’t get your hand into it. ◼ If the glove is missing fingers…