Immune organs a Central immune organs or primary lymphoid organs The site that lymphocytes generate and mature into functional cells Bone marrow and thymus Peripheral immune organs or secondary lymphoid organs and tissues The sites that t and b lymphocytes reside in and respond to antigens spleen, lymph nodes, mucosal or cutaneous lymphoid tissuesImmune organs ◼ Central immune organs or primary lymphoid organs The site that lymphocytes generate and mature into functional cells Bone marrow and Thymus ◼ Peripheral immune organs or secondary lymphoid organs and tissues The sites that T and B lymphocytes reside in and respond to antigens spleen , lymph nodes , mucosal or cutaneous lymphoid tissues