革山院 Definition End stage renal diseases ( esrd) Clinical state in which irreversible loss of endogenous renal function has occurred Patients are permanently dependent on renal replacement therapy to avoid life-threatening uremia CKD Stage 5 Uremia a clinical syndrome reflecting dysfunction of all organ systems due to untreated or undertreated acute or chronic renal failureDefinition • End stage renal diseases (ESRD) – Clinical state in which irreversible loss of endogenous renal function has occurred – Patients are permanently dependent on renal replacement therapy to avoid life-threatening uremia. – CKD Stage 5 • Uremia – A clinical syndrome reflecting dysfunction of all organ systems due to untreated or undertreated acute or chronic renal failure