I Overview of inflammation Definition: Inflammation is the reaction of living tissues to all forms of injury a defensive response of living tissue with a complex reaction in vascularized connective tissue and cellular reaction intended to eliminate the initial cause as well as the necrotic cells and tissuesⅠ. Overview of inflammation Definition: Inflammation is the reaction of living tissues to all forms of injury. A defensive response of living tissue with a complex reaction in vascularized connective tissue and cellular reaction intended to eliminate the initial cause as well as the necrotic cells and tissues