EEG PDS Spike Slow-wave Intracellular recording +20 0 Paroxysmal 2 Depolarization -20 小o Shift -40 -60 -80 3 Ion channels AMPA Receptor Activation NMDA Receptor Activation Sodium Conductance Calcium Conductance Potassium Conductance GABA Inhibition Chloride ConductancePDS