of Fever Pathophysiological Basis of Prevention and Treatment Experiment no Chapter 6 Dysfunction of cell signaling in diseases Objective To understand major pathways for cell signaling.To master the concept of ligand and receptor. TBmaerGproteinsigndlpsthway.Tounderstandtrosineprotensignalpathway.ToundestandguanytMgyclases5gnal Tolea intracellular and nuclear receptor signal pathway. diseases receptor gene mutation and secondary receptor deficit 8l伦amh8beTantGprotenndse inin disease To learn the multiple signaling aberrations in diseases.To master mechanism of cell signaling aberrations due to ligand aodreeptordioeiet n th Teaching contents Experiment no Chapter 7 Cellproliferation,differentiation.apoptosis and the related diseases Objective To understand cell cycle,its control system and its specific checkpoints,and cell proliferation control by extracellular signal tors of cell diffe 一aaencaapgeoesaonnaormaaaonehe Teaching contents Ceameeratandaees CelApOpiossnaneeases Experiment no Chapter 8 Stress and stress-related diseases Thermoregulation of Fever Metabolism and Function Change Pathophysiological Basis of Prevention and Treatment Experiment no Chapter 6 Dysfunction of cell signaling in diseases Objective To understand major pathways for cell signaling. To master the concept of ligand and receptor. To master G protein signal pathway. To understand tyrosine protein signal pathway. To understand guanylyl cyclase signal pathway. To learn intracellular and nuclear receptor signal pathway. To learn the aberrant signal molecules in diseases. To master the aberrant receptors in diseases, including receptor gene mutation and secondary receptor deficit. To learn the aberrant G-protein in diseases. To learn the aberrant intracellular signaling in diseases, To learn the multiple signaling aberrations in diseases. To master mechanism of cell signaling aberrations due to ligand and receptor disorders. To learn the mechanism of tumor, cardiovascular diseases. To understand the relationship between stimulants and pathological effects. Teaching contents Introduction of Signal Transduction System Dysfunction of Cell Signaling in diseases Experiment no Chapter 7 Cell proliferation, differentiation, apoptosis and the related diseases Objective To understand cell cycle, its control system and its specific checkpoints, and cell proliferation control by extracellular signal. To understand deregulation of cell proliferation and diseases. To understand control factors of cell differentiation, it includes intracellular regulators, DNA methylation and extracellular factors. To learn relationship between cell differentiation and tumor. To master the concepts of apoptosis, to understand factors related with cell apoptosis. To understand relation of abnormal cell apoptosis with tumors, autoimmune diseases and heart failure. Teaching contents Cell proliferation and diseases Cell differentiation and diseases Cell Apoptosis and diseases Experiment no Chapter 8 Stress and stress-related diseases