A:10-34 E B:40-81 C:104-180 D:188-208 E:209-481 F:484514 G:519-560 K H:581-624 150 :625-641 J:646-659 250 The IREs K:688-741 B 450 A ]500 A本A本木 5 UUCAUUUUAUUCCI AUG 100200 ●··0。 650 TGGAA AAUGUGAAA5 1837 1823 3 end of human 18S rRNA (1823-1837) FIG. 1. Diagram of RNA secondary structure in the 5'UTR of CVB3(Yang et al., 1997) and the predicted base-pairing model between the yrimidine-lich w act sequence of the viral 5'UTR and the 3 terminal sequence of human 18S rRNA. The ranges of the numbers indicate the ucleotides of respective stem-loop structures, which are labeled A through K. The IRES. authentic initiation codon AUG, and conserved polypyrimidine/AUG tract are marked. The RNA secondary structure of human 18S rRNA 3-end encompassing nucleotide 1823-1837 is based on the published model (Cnan et a/, 1984). Dots between two sequences denote base pairing. The arrows show nucleotides that were changed OCVB3/P565 RNA